Prophet And Loss is a very unique and creative cartoon by Jonathan Bairstow from the MTV series Liquid Television. The music is by Steve Naive & The Love Band.
The video itself is from a longer piece which apparently is a very stylized retelling of Orpheus in the Underworld. This piece aired in season one of Liquid Television (1991-1992) during the third episode.
Prophet and Loss by Jonathan Bairstow
Liquid Television Season 1/Episode 3